|
KMID : 0372919880090010073
|
|
Journal of Biomedical Engineering Research
1988 Volume.9 No. 1 p.73 ~ p.77
|
|
|
Formation of Polyelectrolyte Complex Hydrogel and its Application to Drug Delivery System
|
|
Kim Seon-Ung
|
|
|
Abstract
|
|
|
|
The polymer electrolyte complex hydrogels consisting of poly (methacrylic acid) and poly (4-vinylpyrridine) were formed and 5-flurouracil and pilocarpine drugs were loaded on their hydrogels. Cumulative 5-FU released from PEC hydrogel was affected by the degree of loading and release rate of 5-FU was followed by the monolithic type. Cumulative pilocarpine released from PEC hydrogel increased by ionic interaction between cationic pilocarpine and anionic PMA. Release rate showed the zero order after burst effect.
|
|
|
KEYWORD
|
|
|
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|